Excitation Loss

(biology), cessation or diminution of the passage of nerve impulses into excitable body tissues. Excitation loss arises when there is traumatic damage, or a physical or chemical block of efferent nerve pathways and when corresponding central nervous system structures are destroyed in experiments (on animals) or for therapeutic purposes (in humans). Excitation loss is a unique factor that affects excitable formations and changes the functional state both of nerve centers and of an effector (muscle or gland).