Cache Valley virus

Cache Valley virus

A negative-sense, single-stranded RNA virus of the Bunyaviridae family, genus Orthobunyavirus, Bunyamwera virus group serotype, which was first isolated in Utah and has been found in the rest of the US, especially the Midwest. It is mosquito-borne and causes outbreaks of spontaneous abortion, congenital malformations—e.g., musculoskeletal and CNS defects in sheep during lambing season. It may rarely infect humans, causing severe encephalitis and multiorgan failure.
Vector
Mosquitos—genera Culiseta, Aedes, Anopheles.

Cache Valley virus

Virology A common Bunyamwera virus, isolated in Utah in 1956 and recovered primarily from mosquitos–genera Culiseta, Aedes, Anopheles, and occasionally from vertebrates; in livestock, CVS may cause congenital malformations–musculoskeletal and CNS defects Clinical Rare in humans; CVS infection may be linked to severe encephalitis and multiorgan failure. See Bunyavirus, Encephalitis.