CA 15-3
CA 15-3
A group of mucin-like 300–450-kD glycoproteins that are increased in various cancers—e.g., colon, stomach, gall bladder, pancreas, oesophagus, liver, lung and breast cancers (about one-third of patients with breast cancer who have serum levels above 25 U/mL, which correlates with tumour bulk).Clinical utility
CA 15-3 is theoretically useful for monitoring postoperative tumour recurrence; however, it is less useful in practice.
Specimen
Serum.
Ref range
= 25 U/mL.
Method
Immunoradiometric assay (IRMA).