Cohnheim, Julius

Cohnheim, Julius

(yo͞o`lyo͝os kōn`hīm), 1839–84, German experimental histologist and pathologist. In a relatively brief life Cohnheim made a series of remarkable contributions to the rapidly developing science of pathology. In 1863 he completed important studies on the sugar-forming ferments of the salivary glands and pancreas. Subsequently, he joined Rudolf Virchow at the Pathological Institute in Berlin. Perhaps his most impressive study resulted in the final clarification of the mechanisms of inflammation and suppuration; he demonstrated the migration of leukocytes through blood-vessel walls, thus destroying Virchow's contention that no such passage, or diapedesis, takes place. He also studied venous thrombosis, the embryonic-rest theory of neoplasm formation, atypical leukemias, and experimental tuberculosis.