| 单词 |
dosage compensation |
| 释义 |
DictionarySeedosagedosage compensation
dosage compensation[′dō·sij ‚käm·pən‚sā·shən] (genetics) A mechanism that equalizes the expression in males and females of genes located on the X chromosome, despite their presence in two doses in the homogametic sex and a single dose in the heterogametic sex. A mechanism that equalizes the expression of X-linked and autosomal genes by doubling the expression level of X-linked genes in male Drosophila and in both male and female mammals with their single active X. dosage compensation
dosage compensation a genetical mechanism in which ALLELES of a gene automatically regulate the amount of a useful product produced, so that homozygous-dominant GENOTYPES produce the same amount of gene product as heterozygotes. In this way the two genotypes cannot be distinguished. Dosage compensation occurs regularly in female mammals where one X-chromosome in each cell is thought to become inactivated, leading to equal amounts of gene products in males and females. See INACTIVE-X HYPOTHESIS.LegalSeecompensationFinancialSeeCompensation |
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