alloxan diabetes

al·lox·an di·a·be·tes

experimental diabetes mellitus produced in animals by the administration of alloxan, which damages the insulin-producing islet cells of the pancreas.

alloxan diabetes

An experimental model for type-1 diabetes induced by administration of alloxan, a toxic glucose analogue, which in the presence of intracellular thiols generates reactive oxygen species that selectively destroy pancreatic beta cells.