butyrate:CoA ligase

bu·ty·rate:CoA li·gase

(byū'ti-rāt lī'gās), Fatty acid thiokinase (medium chain), a ligase forming acyl-CoA's from medium-chain fatty acids and CoA with the conversion of ATP to AMP and pyrophosphate. A key step in the activation of fatty acids. Synonym(s): acyl-activating enzyme (2) , butyryl-CoA synthetase, octanoyl-CoA synthetase