estrous cycle
estrous cycle
es′trous cy`cle
n.
单词 | estrous cycle |
释义 | estrous cycleestrous cyclees′trous cy`clen. es·trous cycle(ĕs′trəs)Estrous Cycleestrous cycle[′es·trəs ‚sī·kəl]Estrous Cyclethe aggregate of regularly-recurring changes in the reproductive system of female mammals. Characteristic synchronous changes in the entire female body and especially in the fallopian tubes, uterus, and vagina are governed by the rhythmic processes occurring in the ovaries (the development of the follicles, ovulation, and the formation of the corpus luteum). Each phase of the estrous cycle corresponds to certain changes in the mucous membrane of the vagina and in the cellular composition of the vagina. The estrous cycle lasts 4–5 days in rats and mice, 16–17 days in guinea pigs, 21 days in cows, and 19–23 days in horses. The estrous cycle in rodents is conventionally divided into four stages—diestrus (the quiescent period), proestrus (preparation for estrus), estrus (heat), and metestrus (the luteal phase following estrus). During diestrus, which accounts for approximately one-half of the length of the entire estrous cycle, a smear shows a predominance of mucus and leukocytes. During proestrus, which lasts approximately 12 hours, the smear consists almost entirely of epithelial cells sloughed from the vaginal wall. During estrus, which lasts approximately 27 hours, the smear contains only squamous epithelial cells (anuclear, cornified cells). Animals normally mate only at the beginning of estrus. Metestrus lasts approximately six hours; during this stage the smear shows some leukocytes among the mass of squamous cells. Primates have a menstrual cycle. The estrous cycle is observed only in animals with normally functioning ovaries. After neutering, diestrus sets in, and the other stages of the estrous cycle do not occur. REFERENCEEskin, I. A. Osnovy fiziologii endokrinnykh zhelez, 2nd ed. Moscow, 1975.V. M. SAMSONOVA estrous cyclecycle[si´k'l]![]() ![]() es·trous cy·cleestrous cyclees·trous cy·cle(es'trŭs sī'kĕl)Synonym(s): oestrous cycle. oestrous cycleorestrous cyclea reproductive cycle caused by the cyclic production of gonadotrophic hormones by the PITUITARY GLAND. It occurs in adult female mammals and is only complete when pregnancy does not occur. It lasts from 5 to 60 days, dependent on species.Initially, follicle growth occurs in the ovary as a result of FOLLICLE-STIMULATING HORMONE being secreted by the anterior pituitary This results in increased OESTROGEN production and a thickening of the uterus lining. The build-up of oestrogen results in positive feed-back, causing the anterior pituitary to produce LUTEINIZING HORMONE which in turn brings about ovulation with the formation of a CORPUS LUTEUM, development of the uterine glands, secretion of PROGESTERONE by the corpus luteum (which inhibits FSH production) and a consequent decrease in oestrogen production. Fertilization may occur at this stage and if it does so, pregnancy results. If not, there is a regression of the corpus luteum and a feedback to the anterior pituitary to produce FSH as progesterone decreases. New follicles are formed, the lining of the uterus thins, menstruation (see MENSTRUAL CYCLE occurs in human females and some other primates, and there is a cessation of progesterone secretion and a continued decrease of oestrogen. The cycle then begins again as new follicles grow. Only during the initial period of the cycle, during which ovulation takes place, will the female of most mammalian species copulate (the period of ‘heat'or oestrus). |
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