estrogen receptor assay

Oncology The ER is a protein found in high concentrations in the cytoplasm of breast, uterus, hypothalamus, and anterior hypophysis cells; ER levels are measured to determine a breast CA's potential for response to hormonal manipulation–60% of breast CAs are 'estrogen positive';¹⁄₂ of ER-positive Pts respond favorably to anti-estrogen–tamoxifen citrate therapy, in contrast to <¹⁄₃ of ER-negative Pts. See 'Flare' phenomenon. Cf Progesterone receptor assay.

单词	estrogen receptor assay
释义	estrogen receptor assay estrogen receptor assay Oncology The ER is a protein found in high concentrations in the cytoplasm of breast, uterus, hypothalamus, and anterior hypophysis cells; ER levels are measured to determine a breast CA's potential for response to hormonal manipulation–60% of breast CAs are 'estrogen positive';¹⁄₂ of ER-positive Pts respond favorably to anti-estrogen–tamoxifen citrate therapy, in contrast to <¹⁄₃ of ER-negative Pts. See 'Flare' phenomenon. Cf Progesterone receptor assay.
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