(dō'pă-mēn mon'ō-oks'i-jen-ās), A copper-containing enzyme catalyzing oxidation of ascorbate and 3,4-dihydroxyphenylethylamine simultaneously by O2 to yield norepinephrine, dehydroascorbate, and water; a crucial step in catecholamine metabolism. The enzyme is stimulated by fumarate. Synonym(s): dopamine β-hydroxylase