ACTOBAT

ACTOBAT

Australasian Clinical Trial Of Betamethasone And Thyroid-Releasing-Hormone for Prevention Of Neonatal Respiratory Disease. A trial that asked whether adding thyrotropin-releasing hormone (TRH) to antenatal glucocorticoids in women at risk of preterm delivery would reduce the risk of respiratory distress syndrome (RDS) in their infants.
Conclusion No. Infants experienced increased RDS, greater need for ventilation, and mothers experienced maternal nausea, vomiting, lightheadedness, increased blood pressure.