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digitalisenUK
dig·i·tal·is D0220100 (dĭj′ĭ-tăl′ĭs)n.1. See foxglove.2. A drug prepared from the dried leaves of Digitalis purpurea, used as a cardiac stimulant.
[New Latin Digitālis, genus name of foxglove, from Latin digitālis, of a finger (from the finger-shaped corollas of foxglove), from digitus, finger; see digit.]digitalis (ˌdɪdʒɪˈteɪlɪs) n1. (Plants) any Eurasian scrophulariaceous plant of the genus Digitalis, such as the foxglove, having bell-shaped flowers and a basal rosette of leaves2. (Pharmacology) a drug prepared from the dried leaves or seeds of the foxglove: a mixture of glycosides used medicinally to treat heart failure and some abnormal heart rhythms3. (Pharmacology) any cardiac glycoside, whatever its origin[C17: from New Latin, from Latin: relating to a finger (referring to the corollas of the flower); based on German Fingerhut foxglove, literally: finger-hat or thimble]dig•i•tal•is (ˌdɪdʒ ɪˈtæl ɪs, -ˈteɪ lɪs)
n. 1. any plant of the genus Digitalis, of the figwort family, esp. the foxglove, D. purpurea. 2. the dried leaves of the foxglove used as a heart stimulant. [1655–65; < New Latin digitālis, a name appar. suggested by the German name for the foxglove, Fingerhut literally, thimble; see digital] Thesaurus| Noun | 1. |  digitalis - a powerful cardiac stimulant obtained from foxglovedigitalin, digitalis glycosidedigitoxin - digitalis preparation used to treat congestive heart failure or cardiac arrhythmiadigoxin, Lanoxin - digitalis preparation (trade name Lanoxin) used to treat congestive heart failure or cardiac arrhythmia; helps the heart beat more forcefullycardiac glucoside, cardiac glycoside - obtained from a number of plants and used to stimulate the heart in cases of heart failure | | 2. |  digitalis - any of several plants of the genus Digitalisfoxgloveherb, herbaceous plant - a plant lacking a permanent woody stem; many are flowering garden plants or potherbs; some having medicinal properties; some are pestsgenus Digitalis - genus of Eurasian herbs having alternate leaves and racemes of showy bell-shaped flowerscommon foxglove, Digitalis purpurea, fairy bell, fingerflower, finger-flower, fingerroot, finger-root - tall leafy European biennial or perennial having spectacular clusters of large tubular pink-purple flowers; leaves yield drug digitalis and are poisonous to livestockDigitalis lutea, straw foxglove, yellow foxglove - European yellow-flowered foxglove |
TranslationsdigitalisenUK
digitalis (dĭj'ĭtăl`ĭs), any of several chemically similar drugs used primarily to increase the force and rate of heart contractions, especially in damaged heart muscle. The effects of the drug were known as early as 1500 B.C.; it was later obtained from the foxglove plant, Digitalis purpurea, and from fuchsia (see figwortfigwort,
common name for some members of the Scrophulariaceae, a family comprising chiefly herbs and small shrubs and distributed widely over all continents. The family includes a few climbing types and some parasitic and saprophytic forms.
..... Click the link for more information. ). It was used in the 19th cent. to treat dropsy (edemaedema
, abnormal accumulation of fluid in the body tissues or in the body cavities causing swelling or distention of the affected parts. Edema of the ankles and lower legs (in ambulatory patients) is characteristic of congestive heart failure, but it can accompany other
..... Click the link for more information. ). Digitalislike substances are found in a wide variety of plants and animals, including the poisons of some toad species. Foxglove remains the main source for the drug used medically today. Chemically, digitalis is composed of a sugar (glycoside), a steroid, and a cyclic ester known as a lactone; the pharmacological activity varies according to differences, occurring naturally or introduced synthetically, in the steroid or sugar portions. Common preparations include digitalis, digitoxin, and digoxin, all from foxglove, and ouabain from Strophanthus gratus, the ouabaio tree; these vary both in solubility and in rapidity and duration of effect. Digitalis slows the pulse and slows the conduction of nerve impulses in the heart. By increasing the amount of calcium available to the heart muscle, it improves the force of each heartbeat and increases the amount of blood pumped. It is used in the treatment of congestive heart failurecongestive heart failure,
inability of the heart to expel sufficient blood to keep pace with the metabolic demands of the body. In the healthy individual the heart can tolerate large increases of workload for a considerable length of time.
..... Click the link for more information. and cardiac arrhythmiasarrhythmia
, disturbance in the rate or rhythm of the heartbeat. Various arrhythmias can be symptoms of serious heart disorders; however, they are usually of no medical significance except in the presence of additional symptoms.
..... Click the link for more information. . The mechanism by which it acts to enhance heart muscle contraction is not definitely known. Toxic effects include nausea, vomiting, and visual disturbances. Digitalis (religion, spiritualism, and occult)The dried leaf of the common foxglove (Digitalis purpurea). In 1775 William Witherington, a physician of Birmingham, England, learned of its effectiveness for heart conditions from an old Witch in Shropshire. It was one of several ingredients in her cures, and Witherington managed to isolate digitalis as the main active ingredient. He went on to make many contributions to medicine, and a monument was raised to him at Edgbaston Old Church. The carved decorations on that monument are of the foxglove. Prior to Witherington's application of its use, country wise women used foxglove to treat many maladies, including epilepsy and tuberculosis. Nicholas Culpeper suggests it is "one of the best remedies for a scabby head," while Meyer warns it is "too dangerous for domestic use or self-medication." It certainly is extremely poisonous. Old folk names for it were Witch's Bells and Deadmen's Bells. Three cardiac glucosides have been isolated from digitalis: digitoxin, gitoxin, and gitalin. No synthetic drugs can duplicate the action of the glycosides in foxglove in treating heart failure. Digitalis is recommended in congestive heart failure from any cause, although prolonged use leads to cumulation of the drug because of its slow excretion and destruction. Because of this, side effects can occur, including greater cardiac irregularities. Digitalis a genus of plants of the family Scrophulariaceae. Plants of this genus are perennial or biennial grasses; rarely are they subshrubs or shrubs. The alternate, entire leaves are lanceolate or oblong. The yellow, purple, or yellow-brown flowers are irregular and often large; they are generally in dense terminal racemes. The perianth is five-parted; the bilabiate corolla is campanulate, thimble-shaped, or inflated. The fruit is a capsule. There are approximately 35 species of Digitalis, distributed in Europe, western Asia and northern Africa; the Mediterranean region abounds in Digitalis. Of the six species found in the USSR, four grow only in the Caucasus and two grow in the Caucasus, the European USSR, and Western Siberia. They are found primarily in hardwood and mixed forests and in meadows, thickets, and pastures; they also grow on slopes. All species of Digitalis are poisonous because they contain glycosides, primarily in their leaves. Some species are valuable medicinal herbs. These species include common foxglove (Digitalis purpurea) and yellow foxglove (D. grandiflora), which grow in the European USSR, the Caucasus, and the southern part of Western Siberia; Grecian foxglove (D. lanata), which grows in the Transcarpathian and Odessa oblasts; and such Caucasian species as rusty foxglove (D. ferruginea), D. Schischkinii, and D. ciliata. The glycosides in the leaves regulate heart activity, increase urine elimination, and reduce edema. Medicinal preparations in the form of powders, tinctures, extracts, and neogalenic preparations (such as gitalen) are made from dried leaves, as are secondary glycosides (digitoxin, digoxin). Digitalis preparations are used under strict medical supervision for treating heart disease. Some species of Digitalis are ornamentals. In the USSR, common foxglove is cultivated in Krasnodar Krai and Western Siberia; Grecian foxglove is raised in the Northern Caucasus and the Ukraine. Good yields are obtained on light chernozem soils. Foxglove should be planted on fields that have lain fallow or on which winter crops, annual hay grasses, and well-fertilized industrial and other row crops were previously cultivated. The seeds are generally sown 60 cm apart in the fall or spring; the sowing rate is 6–7 kg of seeds per hectare. Organic and inorganic fertilizers are applied during plowing. In the first and second years, the plants require nitrogen and phosphorous supplements. Under optimum weather conditions and agricultural methods, the leaves may be gathered two or three times in the first year and one or two times in the second. The leaves of annual crops may be harvested first in July or August and later at intervals of one to 1 x/i months. The leaves of biennial foxglove may first be picked between shoot formation and flowering and later during massive flowering. REFERENCESNaperstianka. Moscow, 1954.
Atlas lekarstvennykh rastenii SSSR. Moscow, 1962.
Lekarstvennye rasteniia SSSR kul’tiviruemye i dikorastushchie. Edited by A. A Khotin [et al.]. Moscow, 1967.T. V. EGOROVA digitalis[dij·ə′tal·əs] (pharmacology) The dried leaf of the purple foxglove plant (Digitalis purpurea), containing digitoxin and gitoxin; constitutes a powerful cardiac stimulant and diuretic.
Digitalis[dij·ə′tal·əs] (botany) A genus of herbs in the figwort family, Scrophulariaceae. digitalis1. any Eurasian scrophulariaceous plant of the genus Digitalis, such as the foxglove, having bell-shaped flowers and a basal rosette of leaves 2. a. a drug prepared from the dried leaves or seeds of the foxglove: a mixture of glycosides used medicinally to treat heart failure and some abnormal heart rhythms b. any cardiac glycoside, whatever its origin DigitalisenUK
Digitalis [dij″ĭ-tal´is] a genus of herbs. D. lana´ta yields digoxin and lanatoside and D. purpu´rea, the purple foxglove, has leaves that are a source of digitalis.
digitalis [dij″ĭ-tal´is] dried leaf of Digitalis purpurea; a glycoside" >cardiac glycoside. All drugs prepared from this digitalis leaf are members of the same group and principles of administration are the same, although they vary according to speed of action and potency. Digitalis in its many forms is one of the most frequently prescribed drugs in the United States. It can be very effective in treatment of cardiac conditions, but its therapeutic range is narrow; a therapeutic dose is only about one third less than the dose that will induce toxicity. Moreover, physiologic changes due to age, electrolyte disturbances, renal impairment, metabolic disorders, and certain heart conditions can predispose a patient to digitalis toxicity. Other drugs can also alter the effects of digitalis and lead to toxicity.Signs of Toxicity. Traditionally, nurses have been taught to count the patient's pulse or monitor the apical heartbeat for rate and rhythm before administering a digitalis preparation. A decreased pulse rate of 60 per minute or less is an indication that the drug should be temporarily discontinued. While this is the most typical sign of digitalis intoxication, there frequently are earlier symptoms that deserve attention. Some of the more common complaints expressed by patients who are in the early stages of toxicity are nausea, blurred vision, mental depression, disorientation, and malaise. Objective signs include vomiting, diarrhea, and confusion.Drug Interactions. Unfortunately, most patients who take digitalis also have other drugs prescribed for the management of their illness. The risk of drug interactions and digitalis toxicity increases in proportion to the number of drugs being taken concurrently. One of the most common interactions is with a thiazide diuretic, which can enhance the effect of digitalis and can also lower potassium levels in the blood. Potassium decreases the likelihood of digitalis toxicity and so it is essential that hypokalemia be avoided. Since many patients who take digitalis are on restricted caloric and fluid intake, they cannot adequately replace lost potassium by eating enough potassium-rich foods and need a potassium supplement. Patient Education. There is a danger of complacency about this drug because it is so familiar and so frequently prescribed for self-medication. Without unduly alarming the patient, it is imperative that the action of the drug and its potential for harm if it is not taken as prescribed and with caution are explained. The patient must be informed about the interactions of digitalis with over-the-counter drugs such as antacids and cold remedies that contain ephedrine. The patient should know the signs and symptoms of digitalis toxicity and appreciate the importance of notifying the primary health care provider should any of these signs appear. If the patient does not know how to check the pulse for rate and rhythm, he or she will need to learn how and to learn why it is important to stop taking the drug and notify the physician should the pulse rate fall outside the normal range. There is so much that needs to be known in order to avoid the problems of toxicity inherent in the particular digitalis preparation that it is probably unrealistic to expect patients to remember all that they are told about taking the medication safely. Therefore it is best to give the patient the information in written form and go over the instructions with the patient and a member of the family in order to be sure that the instructions are understood.Digitalis (dij'i-tal'is, -ta'lis), A genus of perennial flowering plants of the family Schrophulariaceae. Digitalis lanata, a European species, and Digitalis purpurea, purple foxglove, are the main sources of cardioactive steroid glycosides used in the treatment of certain heart diseases, especially congestive heart failure; also used to treat tachyarrhythmias of atrial origin. Synonym(s): foxglove [L. digitalis, relating to the fingers; in allusion to the fingerlike flowers] digitalis (dĭj′ĭ-tăl′ĭs)n.1. See foxglove.2. A drug prepared from the dried leaves of Digitalis purpurea, used as a cardiac stimulant.digitalis Homeopathy
A minor homeopathic remedy that is used for heart failure, bradycardia, weakness, nausea evoked by food and hepatitis.digitalis Cardiology A cardiac glycoside first found in foxglove, Digitalis purpurea, now of historic interest; the synthetic derivatives, digoxin and digitoxin are the most popular of the cardiac glycosidesDi·gi·ta·lis (dij'i-tā'lis) A perennial flowering plant that is the main source for some cardioactive steroid glycosides useful in therapy for coronary heart failure and other cardiac disease.
Synonym(s): foxglove. [L. digitalis, relating to the fingers; in allusion to the fingerlike flowers]digitalis A drug used in the treatment of HEART FAILURE. It increases the force of contraction and produces a slower, more regular pulse. The drug is derived from the purple foxglove Digitalis purpurea and is usually given in the form of DIGOXIN.DigitalisA naturally occuring compound used in the preparation of the medication, digoxin, prescribed to increase the heart rate and strengthen the force of the heart's contractions.Mentioned in: Congestive Cardiomyopathy, Edema, Heart FailureDig·i·tal·is (diji-talis, -tālis) A genus of perennial flowering plants; D. lanata, a European species, and D. purpurea, purple foxglove, are the main sources of cardioactive steroid glycosides used to treat some heart diseases, especially congestive heart failure. [L. digitalis, relating to the fingers; in allusion to the fingerlike flowers]digitalisenUK
Related to digitalis: Digitalis purpurea, digoxin, foxglove, digitalis toxicitySynonyms for digitalisnoun a powerful cardiac stimulant obtained from foxgloveSynonyms- digitalin
- digitalis glycoside
Related Words- digitoxin
- digoxin
- Lanoxin
- cardiac glucoside
- cardiac glycoside
noun any of several plants of the genus DigitalisSynonymsRelated Words- herb
- herbaceous plant
- genus Digitalis
- common foxglove
- Digitalis purpurea
- fairy bell
- fingerflower
- finger-flower
- fingerroot
- finger-root
- Digitalis lutea
- straw foxglove
- yellow foxglove
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