bulky disease

bulky disease

term used for large tumors or lymph nodes; usually more resistant to conventional therapy. Synonym(s): bulky lymphadenopathy
A term for a cancer with a considerable tumour burden—‘bulk’; bulky disease generally has a poorer prognosis independent of the histologic grade; a major priority in oncology is to debulk a tumour to optimise chemo- or radiation therapy

bulky disease

Oncology A term for a CA with a considerable tumor burden–'bulk'; BD generally has a poorer prognosis independent of the histologic grade; a major priority in oncology is to debulk a tumor to optimize chemo- or RT. See Debulking operation.