单词 | central dogma |
释义 | central dogmacentral dogmacentral dogmacentral dogma[′sen·trəl ′dȯg·mə]central dogmacen·tral dog·macentral dogmaMolecular biology The pedagogical tenet that translation of a protein invariably follows a chain of molecular command, where DNA acts as the template for both its own replication and for the transcription to RNA–and with subsequent maturation, to mRNA, which then serves as a template for translation into a protein. See DNA, Nucleic acid, Protein, Reverse transcription, RNA, RNA polymerase. Cf Prion.central dogmaThe proposition by Francis Crick (1916–) that, in genetics, the only possible progression was from DNA to RNA to protein. Embarrassingly, the discovery that retroviruses used RNA to make DNA demonstrated the riskiness of pronouncing dogmas in science.central dogmathe hypothesis (based on WEISMANNISM) that genetical information flows only in one direction, from DNA to RNA to PROTEIN, and not in the opposite direction. Thus, in general, changes to protein structures produced by external forces are not inherited. See SOMATIC MUTATION. The hypothesis has, however, been modified to account for the activity of the enzyme REVERSE TRANSCRIPTASE, which transfers information ‘backwards’ from RNA to DNA. |
随便看 |
|
英语词典包含2567994条英英释义在线翻译词条,基本涵盖了全部常用单词的英英翻译及用法,是英语学习的有利工具。