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clotrimazole
clo·trim·a·zole C0419950 (klō-trĭm′ə-zōl′)n. A broad-spectrum antifungal drug, C22H17ClN2, used topically to treat a variety of superficial fungal infections, including candidiasis and ringworm.
[c(h)lo(ro)- + tr(i)- (from its three phenyl groups) + im(id)azole.]TranslationsEncyclopediaSeeantifungal agentclotrimazole
clotrimazole [klo-trim´ah-zōl] a synthetic broad-spectrum antifungal agent applied topically to the skin in the treatment of candidiasis and various forms of tinea, and administered intravaginally in the treatment of vulvovaginal candidiasis and orally in the prevention and treatment of candidiasis of the mouth and throat.clotrimazole (klō-trĭm′ə-zōl′)n. A broad-spectrum antifungal drug, C22H17ClN2, used topically to treat a variety of superficial fungal infections, including candidiasis and ringworm.clotrimazole Infectious disease An antifungal imidazole used topically for candidiasis Adverse effects Nausea, dizziness, diarrhea, changed LFTsclotrimazole A drug effective against a wide range of fungi. It is used in the form of creams, for local application. Brand names are Canesten and Masnoderm. Formulated with BETAMETHASONE it is marketed under the brand name Lotriderm.antifungal agent Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent. |