Clomid
| Noun | 1. | Clomid - a fertility drug (trade name Clomid) that is used to stimulate ovulation and that has been associated with multiple births |
Clomid
Clomid
(klō`mĭd): see fertility drugfertility drug,any of a variety of substances used to increase the possibility of conception and successful pregnancy. Different methods are used to correct or circumvent the many different functional disorders of both males and females that can interfere with conception and
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Clomid
clomiphene citrate (clomifene (UK))
Pharmacologic class: Chlorotrianisene derivative
Therapeutic class: Fertility drug, ovulation stimulant
Pregnancy risk category X
Action
Binds with estrogen receptors in cytoplasm, increasing secretion of folliclestimulating hormone, luteinizing hormone, and gonadotropin in hypothalamus and pituitary gland. These actions induce ovulation.
Availability
Tablets: 50 mg
Indications and dosages
➣ Ovarian failure
Adults: 50 mg/day P.O. for 5 days starting any time in patients with no recent uterine bleeding; or 50 mg/day P.O. starting on fifth day of menstrual cycle. If ovulation doesn't occur, increase to 100 mg/day P.O. for 5 days. Start next course of therapy as early as 30 days after previous course. If patient doesn't respond after three courses, no further doses are recommended.
Off-label uses
• Male sterility (controversial)
Contraindications
• Hepatic disease
• Organic intracranial lesions
• Uncontrolled thyroid or adrenal dysfunction
• Ovarian cyst
• Abnormal uterine bleeding or bleeding of undetermined origin
• Pregnancy
Precautions
None
Administration
• Obtain pregnancy test before therapy begins.
• Be aware that patient should undergo pelvic and eye examinations before starting therapy.
Adverse reactions
CNS: nervousness, insomnia, dizziness, light-headedness
CV: vasomotor flushing
EENT: visual disturbances
GI: nausea; vomiting; abdominal discomfort, distention, and bloating
GU: breast tenderness, ovarian enlargement, multiple pregnancies, birth defects in resulting pregnancies, ovarian hyperstimulation syndrome, uterine bleeding
Interactions
None significant
Patient monitoring
• Monitor patient for bleeding and other adverse reactions.
Patient teaching
See Instruct patient to immediately report signs and symptoms of ovarian hyperstimulation syndrome, including nausea, vomiting, diarrhea, abdominal or pelvic pain, and swelling in hands or legs.
• Tell patient to report bleeding.
• Advise patient not to take drug if she is or may become pregnant.
• Inform patient that drug increases risk of multiple births, which heightens maternal risk.
• As appropriate, review all other significant and life-threatening adverse reactions.
Clomid
(klō′mĭd)Clomid
A brand name for CLOMIPHENE (clomifene).Clomid
- noun
Synonyms for Clomid
noun a fertility drug (trade name Clomid) that is used to stimulate ovulation and that has been associated with multiple births
Synonyms
- clomiphene
- clomiphene citrate
Related Words
- fertility drug
- brand
- brand name
- marque
- trade name