Duchenne's muscular dystrophy

Du·chenne's muscular dystrophy

D0411750 (do͞o-shĕnz′)n. The most common form of muscular dystrophy, caused by a genetic mutation resulting in the absence of the structural protein dystrophin, in which fat and fibrous tissue infiltrate muscle tissue and cause eventual weakening of the respiratory muscles and the myocardium. The disease, which almost exclusively affects males, begins in early childhood and usually causes death before adulthood.

[After Guillaume B.A. Duchenne, (1806-1875), French physician.]

Thesaurus

Noun

Duchenne's muscular dystrophy - the most common form of muscular dystrophy; inheritance is X-linked recessive (carried by females but affecting only males)pseudohypertrophic dystrophydystrophy, muscular dystrophy - any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles

Duchenne's muscular dystrophy

dystrophy

[dis´trah-fe] any disorder due to defective or faulty nutrition, especially muscular dystrophy. adj., adj dystroph´ic.adiposogenital dystrophy adiposity of the feminine type, genital hypoplasia, changes in secondary sex characters, and metabolic disturbances; seen with lesions of the hypothalamus; see also adiposogenital dystrophy.Becker's muscular dystrophy (Becker type muscular dystrophy) a form closely resembling Duchenne's muscular dystrophy, but having a later onset and milder course; transmitted as an X-linked recessive trait.distal muscular dystrophy distal myopathy.Duchenne's muscular dystrophy (Duchenne type muscular dystrophy) The childhood type of muscular dystrophy.facioscapulohumeral muscular dystrophy muscular dystrophy affecting the face, shoulder, and upper arm muscles; called also Landouzy-Dejerine muscular dystrophy.Landouzy-Dejerine dystrophy (Landouzy-Dejerine muscular dystrophy) facioscapulohumeral muscular dystrophy.muscular dystrophy see muscular dystrophy.myotonic dystrophy a rare, slowly progressive, hereditary disease, marked by myotonia followed by muscular atrophy (especially of the face and neck), cataracts, hypogonadism, frontal balding, and cardiac disorders. Called also dystrophia myotonica, myotonia atrophica, and myotonia dystrophica.progressive muscular dystrophy muscular dystrophy.pseudohypertrophic muscular dystrophy muscular dystrophy affecting the shoulder and pelvic girdles, beginning in childhood and marked by increasing weakness, pseudohypertrophy of the muscles, followed by atrophy, and a peculiar swaying gait with the legs kept wide apart. Called also pseudohypertrophic muscular paralysis.reflex sympathetic dystrophy a syndrome of chronic pain that usually develops after a trauma or noxious stimulus, although the nerve injury cannot be immediately identified. The pain is not limited to the distribution of a single nerve and is often out of proportion to the precipitating event. It is most often described as a burning pain, and is accompanied by swelling, sweating, sensitivity to touch, and sometimes changes in tissue growth. Called also chronic or complex regional pain syndrome. Clinical practice guidelines have been published by the Reflex Sympathetic Dystrophy Syndrome Association of America and are available on their web site at http://www.rsds.org or by writing to Reflex Sympathetic Dystrophy Syndrome Association of America, P.O. Box 502, Milford CT 06460.

Duchenne's muscular dystrophy