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bromocriptineenUK
bro·mo·crip·tine B0499350 (brō′mō-krĭp′tēn)n. An ergot alkaloid, C32H40BrN5O5, that is a dopamine antagonist and is used in its mesylate form to treat Parkinson's disease, acromegaly, and excessive prolactin secretion, and to reduce the size of certain pituitary tumors.
[bromo- + (ergo)cryptine, an ergot alkaloid (from German Ergokryptin : Ergo(t), ergot + Greek kruptos, hidden; see cryptic + -in, -in).]bromocriptine (ˌbrəʊməʊˈkrɪptiːn) na dopamine agonist drug which blocks the release of prolactin from the pituitary gland, used in the treatment of Parkinson's diseaseTranslationsbromocriptineenUK
bromocriptine[‚brō·mō′krip‚tēn] (organic chemistry) C32H40BrN5O5 A polypeptide alkaloid that is a derivative of the ergotoxin group of ergot alkaloids and is a dopamine receptor agonist. bromocriptineenUK
bromocriptine [bro″mo-krip´tēn] an ergot alkaloid that acts as a dopamine agonist; used as the mesylate salt to suppress prolactin secretion in the treatment of pituitary prolactinomas and of hyperprolactinemia-associated amenorrhea, galactorrhea, infertility, or male hypogonadism. It is also used as an antidyskinetic, usually in conjunction with levodopa, in the treatment of parkinsonism, and is used as a growth hormone suppressant in the treatment of acromegaly. Administered orally.bromocriptine (brō′mō-krĭp′tēn)n. An ergot alkaloid, C32H40BrN5O5, that is a dopamine antagonist and is used in its mesylate form to treat Parkinson's disease, acromegaly, and excessive prolactin secretion, and to reduce the size of certain pituitary tumors.bromocriptine Endocrinology
An ergoline derivative which reduces pituitary prolactin secretion and size of pituitary tumours.
Indications
Hyperprolactinemia, pituitary tumours, amenorrhoea, female infertility, hypogonadism, acromegaly, Parkinson’s disease, neuroleptic malignant syndrome, type-2 diabetes.
Adverse effects
Orthostatic hypotension, vomiting, vertigo, headaches, upset stomach, coronary vasospasm, pulmonary fibrosis, hepatotoxicity.
Immunology
A dopamine D2-receptor inhibitor which inhibits T-cell-dependent induction of macrophage tumouricidal activity.bromocriptine An ERGOT derivative drug with DOPAMINE-like effects. It is used in the treatment of PARKINSON'S DISEASE and ACROMEGALY and given to prevent LACTATION by inhibiting the secretion of the hormone prolactin by the pituitary gland. A brand name is Parlodel.BromocriptineAlso known as Parlodel, the main drug used to treat galactorrhea by reducing levels of the hormone prolactin.Mentioned in: Galactorrhea, Lactation |