CD59
CD59
CD59
A 65-kD membrane, glycosyl-phosphatidylinositol-anchored complement-neutralising protein encoded by CD59 on chromosome 11p13, which inhibits the complement membrane attack complex, binding to C8 and C9 during assembly of the complex.Normal expression
Most leukocytes and red cells.
Abnormal expression
May be absent in some forms of paroxysmal nocturnal haemoglobinuria.