| 单词 |
cd40lg |
| 释义 |
DictionarySeetumour necrosis factorCD40LG
CD40LG A gene on chromosome Xq26 that encodes of a protein expressed on the surface of T cells which regulates B-cell function by binding CD40 to the B-cell surface. CD40LG is critical for immunoglobulin class switching.
Molecular pathology
A defect in CD40LG is associated with hyper IgM syndrome due to an inability to undergo class switch. |
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