Economo von San Serff disease


E·con·o·mo von San Serff dis·ease

(ē-kon-ō'mō von sahn serf), a unique encephalitis, presumably viral in origin, which followed the influenza pandemic of 1914-1918. Symptoms included ophthalmoplegia and marked somnolence, and in many survivors, the delayed development of Parkinson disease; the basis for postencephalitic Parkinsonism. Synonym(s): encephalitis lethargica, polioencephalitis infectiva