| Acronym | Definition |
|---|
| DS2➣Dark Souls 2 (gaming) |
| DS2➣Dead Space 2 (gaming) |
| DS2➣Dualshock 2 (gamepads) |
| DS2➣Dungeon Siege 2 (video game) |
| DS2➣Design of Systems on Silicon |
| DS2➣Defense Support Services (Lockheed Martin/Day Zimmermann) |
| DS2➣Deca Sports 2 (game) |
| DS2➣Digital Signal 2 - (6.54 Mbps Pipe) |
| DS2➣Decontamination Solution Number Two |
| DS2➣Data Systems Technician Second Class (US Navy Rating) |
| DS2➣Second Version of the Duman-Salehi Bound |