diabetic retinopathy
diabetic retinopathy
Noun | 1. | diabetic retinopathy - retinopathy involving damage to the small blood vessels in the retina; results from chronically high blood glucose levels in people with poorly controlled diabetes |
单词 | diabetic retinopathy | |||
释义 | diabetic retinopathydiabetic retinopathy
diabetic retinopathyretinopathy[ret″ĭ-nop´ah-the]In proliferative diabetic retinopathy new blood vessels form near the optic disk, break through the inner membranous lining, and grow on the vitreous chamber and elsewhere in the retina and may rupture, causing gross vitreous hemorrhage. Additionally, fibrous tissue is generated secondary to the new blood vessel formation, and both the fibrous tissue and the new blood vessels become firmly attached to the posterior vitreous face. As the vitreous humor moves, the blood vessels and fibrous tissue cause tractional pulling on the retina and may result in separation or detachment of areas of retina. Panretinal laser photocoagulation is the definitive therapy. The study of early treatment for diabetic retinopathy proved the efficacy of this procedure in causing regression of the new blood vessels and prevention of vitreous hemorrhage and tractional retinal detachments, the two major causes of vision loss from this form of the disease. di·a·bet·ic ret·i·nop·a·thyIn the U.S., diabetic eye disease is the leading cause of blindness in adults (ages 20-65) and is responsible for 24,000 cases of blindness each year-approximately 25% of all newly reported cases. Within 20 years after the onset of clinical disease, retinopathy occurs in nearly all patients with Type 1 diabetes mellitus (DM) and in more than 60% of patients with Type 2 DM. Retinopathy is already present at the time of diagnosis in 20% of people with Type 2 DM. The principal form is nonproliferative retinopathy, which results directly from degenerative changes in retinal capillaries. Features of this disorder, as observed on funduscopic examination, include microaneurysms; soft or cotton wool exudates, which are actually areas of microinfarction; hard or waxy exudates, which are deposits of lipid and protein from leaking capillaries; and flame or dot-and-blot hemorrhages. A few patients, principally those with Type 1 DM, develop a proliferative retinopathy characterized by neovascularization (proliferation of new capillary loops on the retinal surface). The changes of diabetic retinopathy are most clearly visualized by fluorescein angiography. Either type of retinopathy can impair vision by destroying retinal tissue directly and by predisposing to retinal edema, retinal detachment, and vitreous hemorrhage, but proliferative retinopathy is more rapidly progressive and more likely to lead to blindness without treatment. Controlled clinical studies have shown that maintaining blood glucose levels as near normal as possible at all times in people with DM substantially retards the onset and rate of progression of retinopathy. Laser photocoagulation is effective in arresting neovascularization in proliferative diabetic retinopathy and macular edema. Surgery may be required for treatment of vitreous hemorrhage or retinal tears. diabetic retinopathydiabetic retinopathyOphthalmology A condition characterized by progressive deterioration of the retina with microaneuryms, hemorrhage, neovascularization; it is the major cause of visual impairment in the US < age 60; at 20 yrs, 40% of Pts with type 1 DM and 5% of those with type 2 DM have proliferative DR; clinically significant macular edema occurs in 10–15% of Pts with DM for > 15 yrs Management Glycemic control, photocoagulation, vitrectomydi·a·bet·ic ret·i·nop·a·thy(dī-ă-bet'ik ret'i-nop'ă-thē)diabetic retinopathyA disease of small retinal blood vessels that causes blood leakage (haemorrhages) which may be confined to the RETINA, or which may extend forward into the VITREOUS BODY with serious effects on vision. Fronds of new and fragile blood vessels may develop on the surface of the retina. Treatment is by laser destruction of much of the un-needed periphery of the retina. This is followed by disappearance of new blood vessels.Diabetic retinopathydi·a·bet·ic ret·i·nop·a·thy(dī-ă-bet'ik ret'i-nop'ă-thē)diabetic retinopathy
Words related to diabetic retinopathy
|
|||
随便看 |
|
英语词典包含2567994条英英释义在线翻译词条,基本涵盖了全部常用单词的英英翻译及用法,是英语学习的有利工具。