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单词 daxx
释义

DAXX


DAXX

A gene on chromosome 6p21.3 that encodes a multifunctional protein located in the cytoplasm and nucleus which, as an adaptor protein in the MDM2-DAXX-USP7 complex, regulates RING-finger E3 ligase ubiquitination activity. It is thought to mediate activation of the JNK pathway and apoptosis via MAP3K5, in response to signalling from TNFRSF6 and TGFBR2.

DAXX


AcronymDefinition
DAXXDeath-Associated Protein 6 (also seen as DAP6)
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更新时间:2024/12/23 12:38:56