creatine kinase isoenzymes

cre·a·tine ki·nase i·so·en·zymes

the isoenzymes of creatine kinase. Creatine kinase is a dimer with M (muscle) and/or B (brain) subunits; it exists in three isoenzyme forms: CK-MM, the predominant form, found primarily in skeletal muscle; CK-MB, found in cardiac muscle, tongue, diaphragm, and in small amounts in skeletal muscle; and CK-BB found in the brain, smooth muscle, thyroid, lungs, and prostate. Elevations detected by electrophoresis or other methodologies can be used to help in the differential diagnosis of a variety of disease states, with CK-MB elevations as an important marker following myocardial infarctions, elevations in CK-MM an indicator of muscle disease, and increases in CK-BB an occasional finding following brain infarcts, bowel infarcts, or in the presence of certain malignancies.

单词	creatine kinase isoenzymes
释义	creatine kinase isoenzymes cre·a·tine ki·nase i·so·en·zymes the isoenzymes of creatine kinase. Creatine kinase is a dimer with M (muscle) and/or B (brain) subunits; it exists in three isoenzyme forms: CK-MM, the predominant form, found primarily in skeletal muscle; CK-MB, found in cardiac muscle, tongue, diaphragm, and in small amounts in skeletal muscle; and CK-BB found in the brain, smooth muscle, thyroid, lungs, and prostate. Elevations detected by electrophoresis or other methodologies can be used to help in the differential diagnosis of a variety of disease states, with CK-MB elevations as an important marker following myocardial infarctions, elevations in CK-MM an indicator of muscle disease, and increases in CK-BB an occasional finding following brain infarcts, bowel infarcts, or in the presence of certain malignancies.
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