ciclophilins

ciclophilins

(sik-lō-fil'inz), Intracellular proteins associated with heat shock proteins and other molecules (for example, glucocorticoid receptor). Ciclophilins mediate immunosuppressive actions of antirejection drugs (for example, ciclosporin and FK-506). [ciclosporin + G. philia, affinity, attaction, + -in]