| 单词 | acridines |
| 释义 | acridinesacridinesdyes which can bind to NUCLEIC ACIDS and insert themselves between the adjacent BASES, a process called intercalation. Acridines can inhibit DNA and RNA synthesis and can cause FRAMESHIFT mutations. They are used as MUTAGENS, for example, proflavine (proflavin), as ANTIMICROBIALS, for example acriflavine (acriflavin), and as fluorescent stains for nucleic acids, for example acridine orange. They may also be used to eliminate PLASMIDS from CELLS of BACTERIA, a process known as curing. |
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