英语词汇“bottom-up model”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典-现代词典

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单词	bottom-up model
释义	bottom-up model bottom-up model (programming)A method for estimating the cost of a completesoftware project by combining estimates for each component. bottom-up model bottom-up model One of two proposed mechanisms of spontaneous gastrointestinal tract adenomas. In the bottom up model, a stem cell situated in the base of a crypt acquires mutations in the adenomatous polyposis coli (APC) tumour-suppressor gene, impairing the function of the APC protein. The bottom-up theory holds that adenomas, both familial/hereditary and sporadic, arise from a monoclonal proliferation in the gland crypts (monocryptal adenoma), followed by the multistep process of carcinogenesis.
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