Fas ligand


Fas ligand

a molecule on the surface of cytotoxic T cells that binds to its receptor, Fas, on the surface of other cells, initiating apoptosis in the target cell.

Fas li·gand

(fas lī'gand) A molecule on the surface of cytotoxic T cells that binds to its receptor, Fas, on the surface of other cells, initiating apoptosis in the target cell.
See also: Fas

fas ligand

Abbreviation: FasL
A protein on the surface of activated T cells that binds to Fas receptors on the surface of the same or other T cells and triggers a series of events causing apoptosis. This process is involved in the activation-induced cell death necessary to ensure that autoreactive T cells do not attack “self” antigens. See also: ligand