| 单词 | card17 |
| 释义 | CARD17CARD17A gene on chromosome 11q22.3 that encodes a protein which downregulates procaspase-1/CASP1 activation by inhibiting the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release in response to lipopolysaccharides during inflammation. CARD17 does not induce NF-kappa-B activation during the pro-inflammatory cytokine response. |
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