单词 | chordc1 |
释义 | CHORDC1CHORDC1A gene on chromosome 11q14.3 that encodes a protein that regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. CHORDC1 may act as co-chaperone for HSP90, and may play a role in regulating NOD1 via a HSP90 chaperone complex by inhibiting association of ROCK2 with NPM1. It is involved in stress response and prevents tumuorigenesis. |
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