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单词 choline
释义

choline


cho·line

C0321000 (kō′lēn′)n. A natural amine, C5H15NO2, often classed in the vitamin B complex, that is a constituent of lecithin and other phospholipids and is a precursor of certain biologically important molecules, such as acetylcholine.

choline

(ˈkəʊliːn; -ɪn; ˈkɒl-) n (Biochemistry) a colourless viscous soluble alkaline substance present in animal tissues, esp as a constituent of lecithin: used as a supplement to the diet of poultry and in medicine for preventing the accumulation of fat in the liver. Formula:[(CH3)3NCH2CH2OH]+OH[C19: from chole- + -ine2, so called because of its action in the liver]

cho•line

(ˈkoʊ lin, ˈkɒl in)

n. a viscous fluid, C5H14N + O, that is a constituent of lecithin and a primary component of the neurotransmitter acetylcholine: one of the B complex vitamins. [1865–70; < German Cholin (1862) < Greek chol(ḗ) bile + -in -ine2]
Thesaurus
Noun1.choline - a B-complex vitamin that is a constituent of lecithin; essential in the metabolism of fatB complex, B vitamin, B-complex vitamin, vitamin B, vitamin B complex, B - originally thought to be a single vitamin but now separated into several B vitamins

choline


choline:

see vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
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Choline

A compound, trimethyl-β-hydroxyethylammonium hydroxide, used by the animal organism as a precursor of acetylcholine and as a source of methyl groups. It is a strongly basic hygroscopic substance with the formula

Choline deficiency in animals is associated with fatty livers, poor growth, and renal lesions. It is a lipotropic agent. There is no direct evidence of disease in humans due to choline deficiency, although there have been suggestions that some of the liver, kidney, or pancreas pathology seen in various nutritional deficiency states may be related to choline insufficiency. Choline is found in acetylcholine, which is necessary for nerve impulse propagation, and in phospholipids.

Humans eat 50–600 mg of choline per day, but only excrete 2–4 mg. Thus, conventional tests are of no value in studying choline requirements, and no knowledge of human choline requirements exists. See Acetylcholine

Choline

 

(also 2-hydroxyethyltrimethylammonium hydroxide), [(CH3)3N+CH2CH2OH]OH; occurs as colorless crystals. Choline is readily soluble in water and ethyl alcohol but is insoluble in ether and benzene. It easily forms salts with strong acids, and in aqueous solution it possesses the properties of a strong base.

Choline was first obtained from bile. Widespread in living organisms, it is particularly abundant in egg yolk and in the brain, liver, kidneys, and heart muscles of animals. It is usually regarded as a vitamin of the B complex, although animals and microorganisms are able to synthesize it. Choline is a constituent of phospholipids, such as lecithin and sphingomyelin, and it functions as a donor of methyl groups in the synthesis of methionine. From choline, animals can synthesize acetylcholine, which is one of the most important transmitters of nerve impulses. Choline is a lipotropic agent—that is, it prevents serious liver disorders that may arise as a result of excess accumulations of fat in the liver.

Choline chloride is used in medicine for the treatment of liver diseases and is included in some animal feeds. It is used for analytical purposes because of its ability to form poorly soluble salts with phosphotungstic acid, chloroplatinic acid, and certain other heteropoly acids.

V. A. IAKOVLEV

choline

[′kō‚lēn] (biochemistry) C5H15O2N A basic hygroscopic substance constituting a vitamin of the B complex; used by most animals as a precursor of acetylcholine and a source of methyl groups.

choline


choline

 [ko´lēn] an amine that occurs in phosphatidylcholine and acetylcholine, and is an important methyl donor in intermediary metabolism. Choline is a lipotropic agent, a substance that decreases liver fat content by increasing phospholipid turnover. It was formerly considered to be a B vitamin and is now classified as a pseudovitamin, although it is still sometimes classified as part of the vitamin B complex. Vitamin B12 and folacin are involved in the synthesis of choline.choline acetylase (choline acetyltransferase) an enzyme that brings about the synthesis of acetylcholine.choline magnesium trisalicylate see under trisalicylate.choline salicylate see salicylate.

cho·line

(kō'lēn), agent found in most animal tissues either free or in combination as lecithin (phosphatidylcholine), acetate (acetylcholine), or cytidine diphosphate (cytidine diphosphocholine). It is included in the vitamin B complex. Several salts of choline are used in medicine. Synonym(s): lipotropic factor, transmethylation factor

choline

(kō′lēn′)n. A natural amine, C5H15NO2, often classed in the vitamin B complex, that is a constituent of lecithin and other phospholipids and is a precursor of certain biologically important molecules, such as acetylcholine.

choline

A chemical present in most tissues, either free or combined with acetate (acetylcholine, which is critical for synaptic transmission), cytidine diphosphate or lecithin (phosphatidylcholine); it is included in the vitamin B complex.
Alternative medicine
Some providers of alternative healthcare have recommended choline to manage body odour, convulsions and tardive dyskinesia.

cho·line

(kō'lēn) An amine found in most animal tissues. It is included in the vitamin B complex; as acetylcholine, it is essential for synaptic transmission. Several salts of choline are used in medicine.

choline

One of the B vitamins necessary for the metabolism of fats and the protection of the liver against fatty deposition. The important NEUROTRANSMITTER acetylcholine is formed from it.

choline

an organic base which is a constituent of ACETYLCHOLINE.

cho·line

(kō'lēn) Agent found in most animal tissues either free or in combination as lecithin, acetate, or cytidine diphosphate; included in vitamin B complex.

choline


Related to choline: choline bitartrate, Choline chloride, choline salicylate
  • noun

Words related to choline

noun a B-complex vitamin that is a constituent of lecithin

Related Words

  • B complex
  • B vitamin
  • B-complex vitamin
  • vitamin B
  • vitamin B complex
  • B
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