单词 | african sleeping sickness |
释义 | African sleeping sicknessAfrican sleeping sicknessAfrican sleeping sicknessAfrican sleeping sickness[′af·ri·kən ′slēp·iŋ ′sik·nəs]African sleeping sicknessAfrican sleeping sicknessGam·bi·an try·pan·o·so·mi·a·sisAfrican sleeping sicknessAfrican TrypanosomiasisAn infestation which cripples livestock and affects humans in sub-Saharan Africa; ±50 million Africans are at risk for this haematogenous parasitaemia.Vector Tsetse fly. Types • Rhodesian trypanosomiasis, caused by Trypanosoma brucei rhodesiense, which is more common in East Africa. • Gambian trypanosomiasis, caused by T brucei gambiense, which is more common in West Africa. The trypanosome evades the host’s immune system by frequently changing the proteins on its outer surface, proteins by which the immune system identifies intruders. Clinical findings Acute febrile syndrome, chills, headache, vomiting, pain in extremities, lymphadenopathy, anaemia, depression, fatigue, coma rapidly progressing to death; chronic disease with CNS depression. Sleeping sickness is more common in the West African form and eventually causes death if untreated. Management Symptomatic (airway management, fever, malaise). • East African trypanosomiasis Haematolymphatic stage: suramin; neurologic stage: melarsoprol. • West African trypanosomiasis Haematolymphatic stage: pentamidine or suramin; neurologic stage: melarsoprol or eflornithine. Gam·bi·an try·pa·no·so·mi·a·sis(gam'bē-ăn trī-pan'ō-sō-mī'ă-sis)Synonym(s): chronic trypanosomiasis. Rho·de·sian try·pan·o·so·mi·a·sis(rō-dē'zhŭn trī-pan'ō-sŏ-mī'ă-sis)Synonym(s): acute African sleeping sickness, acute trypanosomiasis. African sleeping sicknessSee TRYPANOSOMIASIS.African sleeping sicknessa fatal infection of the nervous and lymphatic systems that is endemic in certain parts of Africa and is caused by a flagellate protozoan called Trypanosoma, particularly T. brucei gambiense (West Africa) and T. bruceirhodesiense (East Africa). The vector of the flagellate is the tsetse fly Glossina, which also feeds on cattle, the latter acting as a reservoir for the parasite. African sleeping sickness is not to be confused with ENCEPHALITIS which is caused by a virus.Patient discussion about African sleeping sicknessQ. Need Help.I could not enjoy the blessings of nature. I have sleep problem which affects me to a great extent. Hi friends, I need your help. I could not enjoy the blessings of nature. I have sleep problem which affects me to a great extent. Is there any remedy that I can try other than sleeping pills? |
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