Dramamine
enUKDram·a·mine
D0379500 (drăm′ə-mēn′)Dramamine
(ˈdræməˌmiːn)Dram•a•mine
(ˈdræm əˌmin)Trademark.
Noun | 1. | Dramamine - antihistamine and antiemetic (trade name Dramamine) used to treat motion sickness |
单词 | dramamine | |||
释义 | DramamineenUKDram·a·mineD0379500 (drăm′ə-mēn′)Dramamine(ˈdræməˌmiːn)Dram•a•mine(ˈdræm əˌmin)Trademark.
DramamineenUKDramamine[dram´ah-mēn]dimenhydrinatePharmacologic class: Anticholinergic Therapeutic class: Antiemetic, antivertigo agent Pregnancy risk category B ActionPrevents nausea and vomiting by inhibiting vestibular stimulation of chemoreceptor trigger zone and inhibiting stimulation of vomiting center in brain AvailabilityInjection: 50 mg/ml Tablets: 50 mg Tablets (chewable): 50 mg Indications and dosages➣ Prevention and treatment of nausea, vomiting, dizziness, and vertigo Adults and children ages 12 and older: 50 to 100 mg P.O. q 4 hours (not to exceed 400 mg/day), or 50 mg I.M. or I.V. q 4 hours p.r.n. Children ages 6 to 12: 25 to 50 mg P.O. q 6 to 8 hours (not to exceed 150 mg/day), or 1.25 mg/kg I.M. (37.5 mg/m2) q 6 hours p.r.n. Children ages 2 to 6: 12.5 to 25 mg P.O. q 6 to 8 hours (not to exceed 75 mg/day) Contraindications• Hypersensitivity to drug or tartrazine • Alcohol intolerance PrecautionsUse cautiously in: • angle-closure glaucoma, seizure disorders, prostatic hypertrophy • children younger than age 2. Administration• For I.V. use, dilute with dextrose 5% in water or normal saline solution. • Give each 50-mg I.V. dose over 2 minutes. See Don't administer by I.V. route to premature or low-birth-weight infants. Solution contains benzyl alcohol, which can cause fatal "gasping" syndrome. Adverse reactionsCNS: drowsiness, dizziness, headache, paradoxical stimulation (in children) CV: hypotension, palpitations EENT: blurred vision, tinnitus GI: diarrhea, constipation, dry mouth GU: dysuria, urinary frequency Skin: photosensitivity Other: decreased appetite, pain at I.M. site InteractionsDrug-drug. Disopyramide, quinidine, tricyclic antidepressants: increased anticholinergic effects MAO inhibitors: intensified and prolonged anticholinergic effects Other CNS depressants (such as antihistamines, opioids, sedative-hypnotics): additive CNS depression Ototoxic drugs (such as aminoglycosides, ethacrynic acid): masking of signs or symptoms of ototoxicity Drug-diagnostic tests. Allergy skin tests: false-negative results Drug-behaviors. Alcohol use: increased CNS depression Patient monitoring• Assess for lethargy and drowsiness. • Monitor for dizziness, nausea, and vomiting (possible indicators of drug toxicity). Patient teaching• To prevent motion sickness, advise patient to take drug 30 minutes before traveling and to repeat dose before meals and at bedtime. • Instruct patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness. • Caution patient to avoid alcohol and sedative-hypnotics during therapy. • As appropriate, review all other significant adverse reactions and interactions, especially those related to the drugs, tests, and behaviors mentioned above. Dramamine(drăm′ə-mēn′)DramamineenUK
Synonyms for Dramamine
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