英语词汇“foxo1”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

单词	foxo1
释义	FOXO1 FOXO1 The gene on chromosome 13q14.1 which encodes a forkhead family transcription factor that regulates cell responses to oxidative stress. In the presence of KIRT1, it downregulates cyclin D1 and upregulates CDKN1B as required for cell transition from proliferation to quiescence. It may play a role in myogenic growth and differentiation. Molecular pathology FOXO1 translocation with PAX3 has been associated with alveolar rhabdomyosarcoma.
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FOXO1