| 单词 | epstein-barr virus | |||
| 释义 | Epstein-Barr virusEp·stein-Barr virusE0186600 (ĕp′stīn-bär′)Epstein-Barr virus(ˈɛpstaɪn ˈbɑː)Ep′stein-Barr′ vi`rus(ˈɛp staɪn ˈbɑr)n.
Epstein-Barr virusEpstein-Barr virus(EBV), herpesvirus that is the major cause of infectious mononucleosismononucleosis, infectious, acute infectious disease of older children and young adults, occurring sporadically or in epidemic form, also known as mono, glandular fever, and kissing disease. The causative organism is a herpesvirus known as Epstein-Barr virus. ..... Click the link for more information. and is associated with a number of cancers, particularly lymphomaslymphoma, non-Hodgkin's, any cancer of the lymphoid tissue (see lymphatic system) in which the Reed-Sternberg cells characteristic of Hodgkin's disease (the other category of lymphoma) are not present. ..... Click the link for more information. in immunosuppressed persons, including persons with AIDS. Epstein-Barr is a ubiquitous virus, so common that it has been difficult to determine whether it is the cause of certain diseases or whether it is simply there as an artifact. In Third World nations, most children are infected with EBV; in most industrialized nations, about 50% of the people are infected. Research has found that all of the lymphomas associated with AIDS and most lymphomas in other immunocompromised persons are connected with latent EBV infection. EBV has been found in biopsy tissue of patients with Hodgkin's diseaseHodgkin's disease, a type of cancer of the lymphatic system. First identified in 1832 in England by Thomas Hodgkin, it is a type of malignant lymphoma. Incidence peaks in young adults and the elderly. ..... Click the link for more information. , breast cancer, and some smooth muscle tumors. EBV also was formerly suspected as the cause of chronic fatigue syndromechronic fatigue syndrome (CFS), collection of persistent, debilitating symptoms, the most notable of which is severe, lasting fatigue. In other countries it is known variously as myalgic encephalomyelitis (ME), chronic fatigue and immune dysfunction syndrome, and postviral ..... Click the link for more information. (originally named chronic EBV syndrome). Epstein-Barr virusAn antigenically distinct member of the herpesvirus group of viruses, whose genome is DNA. EB virus is the cause of one benign disease (infectious mononucleosis), and is associated with certain types of cancer; however, the great majority of EB virus infections are clinically inapparent. The virus was detected initially by electron microscopy in a small proportion of cells in continuous lymphoblastoid cell lines derived from Burkitt's lymphoma (but particles have not been seen in cells of the tumor itself). The virus also has been detected in cell lines derived from nasopharyngeal carcinomas, a type of cancer found with high frequency in persons from southern China. The virus is found in peripheral blood leukocytes from normal individuals and from patients with infectious mononucleosis. See Infectious mononucleosis, Lymphoma If EB virus is indeed confirmed as having a role in the development of human malignancies, then one major question to be resolved is how a virus so ubiquitous can be involved in so wide a variety of responses. However, it should be recalled that many virus infections (for example, polio virus, hepatitis viruses, certain of the arboviral encephalitides) have a wide spectrum of outcomes, ranging from inapparent infection to severe syndromes. See Animal virus Epstein-Barr virus[¦ep·stīn ¦bär ‚vī·rəs]Epstein-Barr virusEpstein-Barr virus[ep´stīn bahr´]Ep·stein-Barr vi·rus (EBV),(ep'stīn băr), Avoid the mispronunciation ep'stēn.Epstein-Barr virus(ĕp′stīn-bär′)Epstein-Barr virusA double-stranded DNA virus which belongs to the 8-member herpesvirus family. Immature EBV particles are 75–80 nm and appear in the cytoplasm and nucleus of infected host cells; mature infectious particles are 150–200 nm and are cytoplasmic. EBV was first found in a Ugandan child with Burkitt’s lymphoma.Disease associations Infectious mononucleosis is the most common disease associated with EBV infection. Others include aplastic anaemia, Burkitt’s lymphoma (usually African type), hairy leukoplakia, histiocytic sarcoma in patients with kidney transplants and the immunocompromised. EBV facilitates the development of lymphoproliferative disorders (e.g., Hodgkin and non-Hodgkin lymphomas), angiocentric immunoproliferative lesions, Izumi fever, immunoblastic lymphoma, thymic carcinoma, and undifferentiated nasopharyngeal carcinoma. Serologic markers are used to detect active EBV infection and determine the stage of infection. Epstein-Barr virusHuman herpesvirus-4 Virology A double-stranded DNA virus that causes infectious mononucleosis, and belongs to the 8-member herpesvirus family; immature EBV particles are 75-80 nm and appear in the cytoplasm and nucleus; mature infectious particles are 150-200 nm and are cytoplasmic; it is associated with aplastic anemia, Burkitt's lymphoma–usually African type, hairy leukoplakia, histiocytic sarcoma in renal transplants and immunocompromise; EBV facilitate lymphoproliferative disorders–eg, Hodgkin's disease–ID'd by PCR, Southern blot, and in situ hybridization, angiocentric immunoproliferative lesions, NHL, Izumi fever, immunoblastic lymphoma, thymic carcinoma, undifferentiated nasopharyngeal carcinoma–mainland China; several serologic markers are used to detect active EBV infection, and determine the stage of infectionEp·stein-Barr vi·rus(EBV) (ep'stīn bahr vī'rŭs)Synonym(s): human herpesvirus 4. Epstein-Barr virusA member of the herpes family of viruses and the cause of GLANDULAR FEVER (infective mononucleosis). It is also associated with cancer of the back of the nose (nasopharyngeal carcinoma) in Chinese people and with BURKITT'S LYMPHOMA. (Michael Anthony Epstein, English pathologist, b. 1921 and Yvonne M. Barr, English virologist, b. 1932).Epstein-Barr virus (EBV)Epstein,Michael Anthony, English virologist, 1921–.Barr,Yvonne M., English virologist, 1932–.Ep·stein-Barr vi·rus(EBV) (ep'stīn bahr vī'rŭs)Synonym(s): human herpesvirus 4. See EBV Epstein-Barr virus
Synonyms for Epstein-Barr virus
|
|||
| 随便看 |
英语词典包含2567994条英英释义在线翻译词条，基本涵盖了全部常用单词的英英翻译及用法，是英语学习的有利工具。