| 释义 |
cytopathic effect
cytopathic effect[¦sīd·ə¦path·ik i‚fekt] (cell and molecular biology) A change in the microscopic appearance of cells in a culture after being infected with a virus. cytopathic effect
cy·to·path·ic ef·fectdegenerative changes in cells (especially in tissue culture) associated with the multiplication of certain viruses; when, in tissue culture, spread of virus is restricted by an overlay of agar (or other suitable substance) the cytopathic effect may lead to formation of plaque.cytopathic effect The characteristic changes which occur in virally-infected cells in tissue culture, which provides a presumptive means of identifying viruses obtained from a clinical specimen—e.g., adenovirus produces grape-like clusters in HEK cells; rhinovirus produces irregular, rounded “dew drop” changes in culture cells; rubella is diagnosed by exclusion, as it interferes with the CPE of other viruses.See CPE
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