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cytomegalovirus
cy·to·meg·a·lo·vi·rus C0846700 (sī′tə-mĕg′ə-lō-vī′rəs)n. Abbr. CMV Any of a group of herpesviruses that attack and enlarge epithelial cells. Such viruses also cause a disease of infants characterized by circulatory dysfunction and microcephaly.cytomegalovirus (ˌsaɪtəʊˈmɛɡələʊˌvaɪrəs) n (Microbiology) a virus of the herpes virus family that may cause serious disease in patients whose immune systems are compromised. Abbreviation: CMV cy•to•meg•a•lo•vi•rus (ˌsaɪ toʊˌmɛg ə loʊˈvaɪ rəs)
n., pl. -rus•es. a herpesvirus that produces abnormal enlargement of epithelial cells, usu. mildly infectious but a cause of pneumonia in immunodeficient persons and severe systemic damage in the newborn. [1960–65] Thesaurus| Noun | 1. | cytomegalovirus - any of a group of herpes viruses that enlarge epithelial cells and can cause birth defects; can affect humans with impaired immunological systemsCMVherpes virus, herpes - any of the animal viruses that cause painful blisters on the skin |
Translationscytomegalovirus
cytomegalovirus (sī'təmĕg'əlōvī`rəs), member of the herpesvirus family that can cause serious complications in persons with weakened immune systems and infants. A common virus, it is estimated that up to 80% of Americans carry cytomegalovirus by the time they reach adulthood. Most experience no symptoms or mild symptoms such as enlarged lymph nodes, low fever, and fatigue that may or may not be noticed. Cytomegalovirus is present in body fluids (saliva, semen, cervical secretions, and urine) and can be spread from person to person by sexual contact, kissing, or the sharing of food. It can also be transmitted from mother to fetus. The virus usually remains dormant in the body, but it can reactivate and cause serious symptoms in immunologically suppressed patients, such as those with AIDSAIDS
or acquired immunodeficiency syndrome,
fatal disease caused by a rapidly mutating retrovirus that attacks the immune system and leaves the victim vulnerable to infections, malignancies, and neurological disorders. It was first recognized as a disease in 1981.
..... Click the link for more information. , or in infants whose immune systems are not yet fully developed. An estimated 25% of AIDS patients experience CMV infection, often in the form of a viral retinitis that can lead to blindness. Infants can become infected before birth when the mother becomes infected or experiences a recurrence during pregnancy. In a newborn, CMV can be life-threatening, and it can lead to later complications such as cerebral palsy, blindness, hearing problems, mental retardation, and learning disabilities. The antiviral drugs foscarnet and ganciclovir are used to keep active infections under control.cytomegalovirus[¦sīd·ō¦meg·ə·lō′vī·rəs] (virology) An animal virus belonging to subgroup B of the herpesvirus group; causes cytomegalic inclusion disease and pneumonia. Cytomegalovirus
Cytomegalovirus [si″to-meg´ah-lo-vi″rus] a genus of herpesviruses closely related to genus Roseolovirus, containing the single species human herpesvirus 5. It is transmitted by multiple routes and causes infection that is usually mild or subclinical but may be symptomatic (cytomegalic inclusion disease).
cytomegalovirus (CMV) [si″to-meg´ah-lo-vi″rus] any of a subfamily of host-specific herpesviruses infecting humans, monkeys, and rodents, producing unique large cells with inclusion bodies. Opportunistic infection with this virus is common in immunocompromised individuals, causing clinical illnesses such as retinitis" >cytomegalovirus retinitis, pneumonia, esophagitis, colitis, adrenalitis, and hepatitis. It can also cause cytomegalic inclusion disease, a variety of gastrointestinal infections, and encephalitis. Most infections are mild in immunocompetent persons, but it has been associated with a syndrome called mononucleosis" >cytomegalovirus mononucleosis.cytomegalovirus disease cytomegalic inclusion disease.Cy·to·meg·a·lo·vi·rus (CMV), (sī'tō-meg'ă-lō-vī'rŭs), A group of viruses in the family Herpesviridae infecting humans and other animals, many of these viruses having special affinity for salivary glands, and causing enlargement of cells of various organs and development of characteristic inclusions (owl eye) in the cytoplasm or nucleus. Infection of embryo in utero may result in malformation and fetal death. They are all species specific and include salivary virus, inclusion body rhinitis virus of pigs, and others. Synonym(s): visceral disease virus [cyto- + G. megas, big] cytomegalovirus (sī′tə-mĕg′ə-lō-vī′rəs)n. Abbr. CMV Any of a group of herpesviruses that attack and enlarge epithelial cells. Such viruses also cause a disease of infants characterized by circulatory dysfunction and microcephaly.cytomegalovirus A globally distributed herpesvirus (HHV-3) which, in developing nations, is universally acquired in infancy. CMV is transmitted in blood, and rarely is a serious infection unless the host is previously immunocompromised (e.g., as in AIDS, or following bone marrow transplantation) or has leukaemia or lymphoma, in which cases CMV may cause severe pneumonia.TORCH panel TORCH antibody panel Pediatrics A serologic screen for diagnosing prenatal infection; the finding of ↑ IgM in the neonate implies in utero infection by one of the TORCH agents–toxoplasma, rubella, CMV, herpes simplex, which is then characterized by measuring specific IgM levels. TORCH agents
Toxoplasmosis may cause periventricular microglial nodules, thrombosis and necrosis; obstruction of cerebral foramina causes hydrocephalus; with prolonged survival, there is intracranial calcification, hepatocellular, adrenal, pulmonary, cardiac necrosis and extramedullary hematopoiesis Rubella may cause LBW, hepatosplenomegaly, petechiae and purpura, congenital heart disease, cataracts, microophthalmia and microcephaly; CNS symptoms include lethargy, irritability, dystonia, bulging fontanelles and seizures. See Congenital rubella syndrome. Cytomegalovirus may cause hepatosplenomegaly, hyperbilirubinemia, neonatal thrombocytopenia, microcephaly and a mortality of 20-30%; later manifestations include mental retardation, deafness, psychomotor delays, dysodontogenesis, chorioretinitis, learning disabilities; ± 33 000 congenital cases/year–US, of which 10% are symptomatic Herpes simplex may cause prematurity, and becomes symptomatic after the first week of life; CNS symptoms include irritability, seizures, chorioretinitis, hydrocephalus, flaccid or spastic paralysis, opisthotonos, decerebrate rigidity and coma; in neonatal HSV infection, no deaths occur in those with localized disease, 15% die if encephalitis is present and 57% die if HSV is disseminated, potentially evoking DIC NEJM 1991; 324:450 Syphilis–an optional 'TORCH' Congenital syphilis has ↑ to epidemic rates in the urban US since the mid-1980s; the clinical findings are nonspecific and include fever, lethargy, failure to thrive, and irritability
cy·to·meg·a·lo·vi·rus (CMV) (sī'tō-meg'ă-lō-vī'rŭs) A group of herpesviruses infecting humans and other animals, many having special affinity for salivary glands, and causing development of characteristic inclusions in the cytoplasm or nucleus. Most infections are asymptomatic, but if symptoms are present, they manifest as mononucleosislike illness. Congenital infection may cause malformation or fetal death; infection in immunocompromised persons may be life-threatening.
Synonym(s): human herpesvirus 5. [cyto- + G. megas, big]Cytomegalovirus (CMV)A common human virus causing mild or no symptoms in healthy people, but permanent damage or death to an infected fetus, a transplant patient, or a person with HIV.Mentioned in: Antiviral Drugs, Bone Marrow Transplantation, Cytomegalovirus Antibody Screening Test, Maternal to Fetal InfectionsPatient discussion about CytomegalovirusQ. What is it CMV during pregnancy? can i infect with that? A. CMV is a virus. What you refer to is infection with CMV, either the initial infection, or re-activation of latent (dormant) virus that resides in the mother's body during pregnancy.
The dangers are that CMV will infect the fetus, which may cause malformations, particularly growth restriction and hearing impairment.
You may read more here:
www.nlm.nih.gov/medlineplus/cytomegalovirusinfections.html
Q. What is it CMV during pregnancy ? can i infect with that? A. CMV or cytomegalovirus (http://en.wikipedia.org/wiki/Cytomegalovirus) is a virus that can cause disease (i.e. infectious mononucleosis, http://en.wikipedia.org/wiki/Infectious_mononucleosis) in everyone, not only pregnant women. The problem is that when a pregnant woman is infected in CMV for the first time of her life during pregnancy, CMV can cause malformations and problems with the baby, including hearing impairment and others (see also TORCHES: http://en.wikipedia.org/wiki/TORCH_infections).
Q. Do you want to end because of a vaccination in a wheel chair? It is already about 12 years ago. I met a mother with her kids. One came always in a wheel chair to the services. His terrible story is still in my mind. It could be shown, that because of a vaccination he got thecytomegalovirus infection (CMV) and then spastic paralysis.A. Corrigendum: If you know somebody speaking German and English who could... More discussions about CytomegalovirusSee CMV
See CMVcytomegalovirus
Related to cytomegalovirus: Cytomegalovirus infection, Epstein Barr virusSynonyms for cytomegalovirusnoun any of a group of herpes viruses that enlarge epithelial cells and can cause birth defectsSynonymsRelated Words |