| 释义 |
DictionarySeedegenerationEncyclopediaSeeDegenerationcorticobasal degeneration
corticobasal degenerationa rare, progressive disease (considered by some a variant of Parkinson disease) involving both cerebral cortex and extrapyramidal structures; clinically manifest as disturbances of voluntary movements and rigidity; pathologic characteristics include degeneration of the cerebral cortex with balloon neurons and degeneration of the substantia nigra; apraxia, cortical sensory loss, myoclonus, and phantom limb syndrome have been reported.corticobasal degeneration A rare idiopathic cerebrodegenerative “tauopathy” which is difficult to diagnose in vivo (less than 25% are correctly diagnosed), as many patients carry the diagnosis of progressive supranuclear palsy whilst alive. Of those with a clinical diagnosis of corticobasal degeneration in vivo, 75% had another diagnosis at autopsy; again, many had progressive supranuclear palsy.cor·ti·co·ba·sal de·gen·er·a·tion (kōr'ti-kō-bā'săl dĕ-jen'ĕr-ā'shŭn) A rare, progressive disease involving both cerebral cortex and extrapyramidal structures; clinically manifested as disturbances of voluntary movements and rigidity; pathologic characteristics include degeneration of the cerebral cortex with balloon neurons and degeneration of the substantia nigra. corticobasal degenerationA neurological disorder in which brain cells atrophy and die in the basal ganglia and the cortex of the brain. The disease produces symptoms similar to those found in Parkinson's disease but does not respond to parkinsonian medications. See also: degenerationAcronymsSeeCBD |