elastin
e·las·tin
E0066100 (ĭ-lăs′tĭn)elastin
(ɪˈlæstɪn)e•las•tin
(ɪˈlæs tɪn)n.
Noun | 1. | elastin - a fibrous scleroprotein found in elastic tissues such as the walls of arteries |
单词 | elastin | |||
释义 | elastine·las·tinE0066100 (ĭ-lăs′tĭn)elastin(ɪˈlæstɪn)e•las•tin(ɪˈlæs tɪn)n.
Elastinelastin[i′las·tən]Elastinthe scleroprotein that is the chief constituent of elastic fibers of connective tissue. Elastin is especially abundant in the cervical ligaments and the aortic walls (about 40 percent of the dry mass). The amount of elastin in lung tissue increases with age from 0.05 to 15 percent of the dry mass. Elastin is insoluble (even when heated) in water, dilute saline solutions, acids, and alkalies. It contain a large number of amino acid radicals with nonpolar side chains, which appear to be responsible for the high elasticity of its fibers. Like collagen, elastin is rich in glycine and proline. Elastin can be broken down only with difficulty by proteolytic enzymes. It is digested in the digestive tract mainly as a result of the action of the enzyme elastase. Elastin is found in all vertebrates except cyclostomes; it is absent in invertebrates. REFERENCESHaurowitz, F. Khimiia i funktsii belkov, 2nd ed. Moscow, 1965. (Translated from English.)Elastin and Elastic Tissue. New York–London, 1977. elastinelastin[e-las´tin]e·las·tin(ē-las'tin), [MIM*130160]elastin(ĭ-lăs′tĭn)elastinA fibrous protein which is similar to collagen (in that one-third of the amino acids are glycine) with abundant proline, valine, and arginine, and which is formed by cross-linking small globular subunits to lysine residues. Elastin’s elasticity is ideally suited for its prominent role in arterial walls, vocal cords, alveolar septa, and ligaments, and has an amorphous wavy appearance by light microscopy. Defects in the cross-linking in elastin’s unique beta spiral, as well as increases or decreases in elastin, are implicated in coronary heart disease, emphysema, type-V Ehlers-Danlos syndrome, Menke’s kinky hair disease, pseudoxanthoma elasticum, and X-linked cutis laxa.e·las·tin(ĕ-las'tin)Synonym(s): elasticin. elastinthe major protein found in ELASTIC FIBRES, responsible for the extensible and resilient nature of tissues, such as the skin, lung and larger blood vessels.elastin
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