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DictionarySeeCPTcamptothecin
camptothecin[‚kam·tō′thē·sən] (pharmacology) An alkaloid belonging to the family of drugs called topoisomerase inhibitors which is used as an anticancer drug, it is the first known naturally produced DNA topoisomerase inhibitor and was originally isolated from the Chinese tree Camptothecin acuminate. camptothecin
camp·to·the·cin (kamp'tō-thek'in), Plant alkaloids consisting of a pentacyclic structure with a lactone ring; inhibitors of topoisomerase I, that is, topotecan and irinotecan (CPT-11). [Camptotheca, genus name of botanic source] camp·to·the·cin (kamp'tō-thē'sin) Plant alkaloids consisting of a pentacyclic structure with a lactone ring; inhibitors of topoisomerase I, i.e., topotecan and irinotecan (CPT-11). [Camptotheca, genus name of botanic source]camptothecin (kămp″tō-thē′sĭn), CPTAn inhibitor of the enzyme topoisomerase I. Medications derived from this agent (including irinotecan and topotecan) are used to treat a variety of cancers. |