Chemotherapeutic Agent

the name given to various groups of drugs used in chemotherapy and chemoprophylaxis. Chemotherapeutic agents include substances of natural origin (for example, antibiotics) and synthetic preparations (for example, sulfanilamides, nitrofurans, and para-aminosalicylic acid). Antimicrobial, antiparasitic, and antineoplastic chemotherapeutic agents are distinguished. With the discovery and use of sulfanilamides (G. Domagk) and antibiotics (A. Fleming, H. Florey, and E. Chain) in the 1930’s and 1940’s, chemotherapeutic agents became the principal means of treating infectious diseases. In the 1940’s and 1950’s nitrogen mustard and many other agents became important in the treatment of malignant tumors.

chemotherapeutic agent

An agent used to treat cancer administered in regimens of one or more cycles, combining two or more agents over a period of days to weeks. Such agents are toxic to cells with high proliferative rates—e.g., to the cancer itself, but also to the GI tract (causing nausea and vomiting), bone marrow (causing various cytopenias) and hair (resulting in baldness).
Examples
Busulphan, cisplatin, cyclophosphamide, MTX, daunorubicin, doxorubicin, melphalan, vincristine, vinblastine, chlorambucil.

chemotherapeutic agent

An agent used to treat CA, administered in 'regimens'-one or more 'cycles' that combine 3 or more agents over wks; CAs are toxic to any cell with a high rate of proliferation–the CA itself, the GI tract–causing N&V, BM–cytopenias, and hair—alopecia Examples Busulphan, cisplatin, cyclophosphamide, MTX, daunorubicin, doxorubicin, melphalan, vincristine, vinblastine, chlorambucil. See Immunosuppressive agents.

che·mo·ther·a·peu·tic a·gent

(kēmō-thār-ă-pyūtik ājĕnt) Chemical that is used for therapeutic reasons.

单词	chemotherapeutic agent
释义	DictionarySeechemotherapy Chemotherapeutic Agent Chemotherapeutic Agent the name given to various groups of drugs used in chemotherapy and chemoprophylaxis. Chemotherapeutic agents include substances of natural origin (for example, antibiotics) and synthetic preparations (for example, sulfanilamides, nitrofurans, and para-aminosalicylic acid). Antimicrobial, antiparasitic, and antineoplastic chemotherapeutic agents are distinguished. With the discovery and use of sulfanilamides (G. Domagk) and antibiotics (A. Fleming, H. Florey, and E. Chain) in the 1930’s and 1940’s, chemotherapeutic agents became the principal means of treating infectious diseases. In the 1940’s and 1950’s nitrogen mustard and many other agents became important in the treatment of malignant tumors. chemotherapeutic agent chemotherapeutic agent An agent used to treat cancer administered in regimens of one or more cycles, combining two or more agents over a period of days to weeks. Such agents are toxic to cells with high proliferative rates—e.g., to the cancer itself, but also to the GI tract (causing nausea and vomiting), bone marrow (causing various cytopenias) and hair (resulting in baldness). Examples Busulphan, cisplatin, cyclophosphamide, MTX, daunorubicin, doxorubicin, melphalan, vincristine, vinblastine, chlorambucil. chemotherapeutic agent An agent used to treat CA, administered in 'regimens'-one or more 'cycles' that combine 3 or more agents over wks; CAs are toxic to any cell with a high rate of proliferation–the CA itself, the GI tract–causing N&V, BM–cytopenias, and hair—alopecia Examples Busulphan, cisplatin, cyclophosphamide, MTX, daunorubicin, doxorubicin, melphalan, vincristine, vinblastine, chlorambucil. See Immunosuppressive agents. che·mo·ther·a·peu·tic a·gent (kēmō-thār-ă-pyūtik ājĕnt) Chemical that is used for therapeutic reasons. FinancialSeeagent
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