epinephrine reversal

ep·i·neph·rine re·ver·sal

the fall in blood pressure produced by epinephrine when given following blockage of α-adrenergic receptors by an appropriate drug such as phenoxybenzamine; the vasodilation reflects the ability of epinephrine to activate β-adrenergic receptors that, in vascular smooth muscle, are inhibitory; in the absence of α-receptor blockade, the β-receptor activation by epinephrine is masked by its predominant action on vascular α-receptors, which causes vasoconstriction. Synonym(s): adrenaline reversal

ep·i·neph·rine re·ver·sal

(epi-nefrin rĕ-vĕrsăl) The fall in blood pressure produced by epinephrine when given following blockage of α-adrenergic receptors by an appropriate drug such as phenoxybenzamine; the vasodilation reflects the ability of epinephrine to activate β-adrenergic receptors that, in vascular smooth muscle, are inhibitory.