Noun | 1.epilepsia major - epilepsy in which the attacks involve loss of consciousness and tonic spasms of the musculature followed by generalized jerkinggeneralized epilepsy, grand mal, grand mal epilepsyepilepsy - a disorder of the central nervous system characterized by loss of consciousness and convulsions | | 2.epilepsia major - a seizure during which the patient becomes unconscious and has convulsions over the entire bodygeneralized seizure, grand malepileptic seizure - convulsions accompanied by impaired consciousness |