down-regulation

[down-reg-u-la´shun] a decrease in the number of receptors" >receptors for a chemical or drug on cell surfaces in a given area, usually due to long-term exposure to the agent. See also up-regulation" >up-regulation.

down-reg·u·la·tion

(down-reg'yū-lā'shŭn), Development of a refractory or tolerant state consequent on repeated administration of a pharmacologically or physiologically active substance; often accompanied by an initial decrease in affinity of receptors for the agent and a subsequent diminution in the number of receptors.

单词	down-regulation
释义	DictionarySeedownregulation down-regulation down-regulation [down-reg-u-la´shun] a decrease in the number of receptors" >receptors for a chemical or drug on cell surfaces in a given area, usually due to long-term exposure to the agent. See also up-regulation" >up-regulation. down-reg·u·la·tion (down-reg'yū-lā'shŭn), Development of a refractory or tolerant state consequent on repeated administration of a pharmacologically or physiologically active substance; often accompanied by an initial decrease in affinity of receptors for the agent and a subsequent diminution in the number of receptors.
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