| 单词 | alglucerase |
| 释义 | alglucerasealglucerase[al-gloo´ser-ās″]algluceraseA modified form of beta-glucerebrosidase that catalyses the hydrolysis of glucocerebroside in reticuloendothelial system lysosomes, which is the most effective therapy for type-1 Gaucher disease, resulting in decreased hepatospenomegaly, haematologic defects, increased bone mineralisation and reversal of cachexia seen in these patients.algluceraseCeredase® A monomeric 497 AA glycoprotein and modified form of β-glucerebrosidase, which catalyzes the hydrolysis of glucocerebroside in reticuloendothelial system lysosomes, which is produced by genetic engineering; alglucerase is the most effective therapy for type 1 Gaucher disease, resulting in ↓ hepatospenomegaly, hematologic defects, ↑ bone mineralization, and reversal of cachexia Cost Very high. See Gaucher disease, 'Orphan drug. '. |
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