释义 |
coregulators co·reg·u·la·tors (kō'reg'yū-lā-tŏrz), Nuclear proteins that participate in the regulation of transcription of genes that are responsive to ligand-dependent transcription factors. Distinguished loosely into coactivators or corepressors depending on the direction of coregulation. Defective coregulators have been associated with human disease. See also: coactivator, corepressors. [co- + regulator] |