单词 | amphiregulin |
释义 | amphiregulinamphiregulinA 84-residue bifunctional cell growth-modulating glycoprotein encoded by AREG on chromosome 4q13-q21, which inhibits the growth of certain tumours (e.g., epidermal cancer) and stimulates the proliferation of fibroblasts. The carboxy-terminal half of amphiregulin has considerable structural homology with epidermal growth factor and binds to its receptor. |
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