calcitriol

cal·ci·tri·ol

C5027950 (kăl′sĭ-trī′ôl′, -ōl′)n. The active metabolite of vitamin D, C₂₇H₄₄O₃, that is synthesized in the kidneys and liver from vitamin D₂ or vitamin D₃ and acts as a calcium-regulating hormone. A synthetic form is used as a drug to treat hypocalcemia, bone disease caused by renal failure, and, in topical preparations, psoriasis.

[calci- + triol.]

Translations

calcitriol

[kal´sĭ-tri´ol] 1,25-dihydroxycholecalciferol; a form of vitamin D" >vitamin D used as a calcium regulator in the management of hypocalcemia in conditions such as rickets, osteodystrophy, hypoparathyroidism, and complications of dialysis" >renal dialysis; administered orally or intravenously.

cal·ci·tri·ol

(kal'si-trī'ol), 1α,25-Dihydroxycholecalciferol (thus, a 1,3,25-triol); formation of calcitriol is the second step in the biologic conversion of vitamin D₃ to its active form; it is more potent than calcidiol.

calcitriol

A form of vitamin D3 which promotes intestinal absorption of Ca2+, increases renal tubular reabsorption of Ca2+ and reduces Ca2+ resorption by bone.

Indications
Postmenopausal and corticosteroid-induced osteoporosis, hypocalcaemia, hypoparathyroidism, osteomalacia, rickets, renal osteodystrophy, chronic renal dialysis.
Adverse effects
Nausea, vomiting, constipation, anorexia, headache, thirst, sweating, polyuria—all due to hypercalcaemia.

calcitriol

A vitamin D analogue drug used in the treatment of low calcium levels resulting from kidney disease. Brand names are Calcijex, Rocatrol and Silkis.

单词	calcitriol
释义	calcitriol cal·ci·tri·ol C5027950 (kăl′sĭ-trī′ôl′, -ōl′)n. The active metabolite of vitamin D, C₂₇H₄₄O₃, that is synthesized in the kidneys and liver from vitamin D₂ or vitamin D₃ and acts as a calcium-regulating hormone. A synthetic form is used as a drug to treat hypocalcemia, bone disease caused by renal failure, and, in topical preparations, psoriasis. [calci- + triol.] Translations calcitriol calcitriol [‚kal·sə′trī‚ōl] (biochemistry) 1,25-dihydroxycholecalciferol, the form of vitamin D that is involved in intestinal absorption of Ca²⁺and Ca²⁺resorption by bone. calcitriol calcitriol [kal´sĭ-tri´ol] 1,25-dihydroxycholecalciferol; a form of vitamin D" >vitamin D used as a calcium regulator in the management of hypocalcemia in conditions such as rickets, osteodystrophy, hypoparathyroidism, and complications of dialysis" >renal dialysis; administered orally or intravenously. cal·ci·tri·ol (kal'si-trī'ol), 1α,25-Dihydroxycholecalciferol (thus, a 1,3,25-triol); formation of calcitriol is the second step in the biologic conversion of vitamin D₃ to its active form; it is more potent than calcidiol. calcitriol A form of vitamin D3 which promotes intestinal absorption of Ca2+, increases renal tubular reabsorption of Ca2+ and reduces Ca2+ resorption by bone. Indications Postmenopausal and corticosteroid-induced osteoporosis, hypocalcaemia, hypoparathyroidism, osteomalacia, rickets, renal osteodystrophy, chronic renal dialysis. Adverse effects Nausea, vomiting, constipation, anorexia, headache, thirst, sweating, polyuria—all due to hypercalcaemia. calcitriol A vitamin D analogue drug used in the treatment of low calcium levels resulting from kidney disease. Brand names are Calcijex, Rocatrol and Silkis.
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