demyelinating polyneuropathy

de·my·e·li·nat·ing pol·y·neu·rop·a·thy

a type of polyneuropathy in which almost solely the peripheral nerve myelin is affected; can be familial (for example, Charcot-Marie-Tooth disease, type 1) or acquired (for example, Guillain-Barré syndrome); on motor nerve conduction studies, manifested as conduction slowing or block. Synonym(s): segmental demyelinating polyneuropathy